{"version":1,"kind":"Article","sha256":"","slug":"605","location":"","dependencies":[],"doi":"10.54294/i1vy9q","frontmatter":{"title":"Multiple Sclerosis Lesion Segmentation Using Statistical and Topological Atlases","abstract":"This paper presents a new fully automatic method for segmentation of\r\nbrain images that possess multiple sclerosis (MS) lesions.\r\nMultichannel magnetic resonance images are used to delineate multiple\r\nsclerosis lesions while segmenting the brain into its major\r\nstructures. The method is an atlas based segmentation\r\ntechnique employing a topological atlas as well as a statistical\r\natlas. An advantage of this approach is that all segmented structures\r\nare topologically constrained, thereby allowing subsequent processing\r\nwith cortical unfolding or diffeomorphic shape analysis techniques.\r\nValidation on data from two studies demonstrates that the method has\r\nan accuracy comparable with other MS lesion segmentation methods,\r\nwhile simultaneously segmenting the whole brain.","license":"You are licensing your work to Kitware Inc. under the\nCreative Commons Attribution License Version 3.0.\n\nKitware Inc. agrees to the following:\n\nKitware is free\n * to copy, distribute, display, and perform the work\n * to make derivative works\n * to make commercial use of the work\n\nUnder the following conditions:\n\\\"by Attribution\\\" - Kitware must attribute the work in the manner specified by the author or licensor.\n\n * For any reuse or distribution, they must make clear to others the license terms of this work.\n * Any of these conditions can be waived if they get permission from the copyright holder.\n\nYour fair use and other rights are in no way affected by the above.\n\nThis is a human-readable summary of the Legal Code (the full license) available at\nhttp://creativecommons.org/licenses/by/3.0/legalcode","keywords":["Tissue Classification","Multiple Sclerosis","Magnetic Resonance Imaging"],"authors":[{"name":"Shiee, Navid","email":"navid_shiee@yahoo.com","affiliations":["Johns Hopkins University"],"corresponding":true},{"name":"Bazin, Pierre-Louis","affiliations":[]},{"name":"Pham, Dzung L.","affiliations":[]}],"date_submitted":"2008-10-02 16:13:54","external_publication_id":605,"revision_cids":["bafkreihhkzkkc4wuqtih7haleiyos46wf2kl3ykpw7vgjepn5jf2yufkpu"]},"mdast":{"type":"root"},"downloads":[{"url":"https://ipfs.desci.com/ipfs/bafkreicphmjulxrif4mifrr5yvpxsohvfzsipw3xzdio44wscmrqdmnbmy","title":"root/insight-journal-metadata.json","filename":"insight-journal-metadata.json","extra":{"size_bytes":9686,"type":"file"}},{"url":"https://ipfs.desci.com/ipfs/bafkreihfl6xzgx2veiqvjsyvqfp4qb3dm53sv7hiwzaryriqwliu7pbzbu","title":"root/reviews.md","filename":"reviews.md","extra":{"size_bytes":1118,"type":"file"}},{"url":"https://dweb.link/ipfs/bafkreibl5y5jwccbkfoex7tzncvihaohda7c3fm6tcogzffro4ubal6c3a","title":"root/article.pdf","filename":"article.pdf","extra":{"size_bytes":307949,"type":"file"}}],"references":{"cite":{"order":["ref1","ref2","ref3","ref4","ref5","ref6","ref7","ref8","ref9","ref10","ref11","ref12","ref13","ref14","ref15","ref16","ref17"]},"data":{"ref1":{"label":"ref1","enumerator":"1","html":"Multiple sclerosis+27+1+78+85+2007+R.H.B. 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